LGBTQ+ people are met with a variety of intersecting experiences such as racism, discrimination and stigma that can lead to elevated rates of substance use and co-occurring psychiatric disorders. The Opioid Response Network’s Sexuality and Gender Diversity Workgroup supports the coalition’s overarching goal of providing education and training in the prevention, treatment and recovery of opioid and stimulant use disorders to LGBTQ+ communities in a culturally responsive and structurally competent manner. To achieve this mission, this workgroup provides resources as well as guidance on education and training activities.